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Trifexis side effects

Pet owners are reporting the following as side effects of Trifexis: seizures, shaking, lethargy, falling asleep while sitting up, no appetite, no energy and more.

Symptoms may present within hours of taking the pills while others experience side effects after several doses.

My personal clients have seen shaking, lethargy, possible seizure and aggression. Yes, one of the ingredients in this pills IS linked to aggression!

Intervention for Trifexis

Some pet owners have reported their vet did blood work and administered fluids. Others decided to try a natural supplement to detox their dogs liver by using a Liver cleanse supplement.*Your dog’s weight plays a role in the proper dosage. For example, My vet said my dog (approx. 75 lbs) can have half the dosage I would take. I do this twice a year with him for general maintenance.

If you prefer a dog specific liver detox, liquid version, this one has many beneficial ingredients.

Although I am for the natural approach, you must decide what is best for your pet based on their symptoms and the severity of their symptoms. Report reactions: If you suspect your pet has suffered from adverse reactions, you may report it to FDA at 1-800-FDA-VETS or visit their website to file your complaint.

Going forward there are a few things you can do to reduce risk factors.

Access your dog’s lifestyle

A few factors may help you in making a decision on how to proceed in regards to heartworm.

  • Heartworm lifecycle
  • Reported cases of heartworm in your area
  • Preventatives: Alternatives & conventional

Here is an article by a holistic vet that discusses heartworm along with a map of reported cases across The United States.

Heartworm preventatives vs. treatment

Keep in mind the more things the medicine treats (fleas, heartworm and parasites) the more chemicals we are introducing into our pets system.

For natural flea preventatives, this shampoo can be used instead of using topical treatments aka spot on’s. Here is a spray to use inside your homeand dog skin spray to use for bites, cuts or hotspots.

I should mention one person reported their pet tested heartworm positive while being on Trifexis.

I know of one holistic vet who treated a dog successfully with a black walnut tincture. The dog was tested several times over a few years and it never came back heartworm positive again.

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Disclaimer: The information contained in this web site is provided for general informational purposes only. It is not intended to diagnose or treat your pet. If your pet has a medical problem, please seek medical attention from your veterinarian. Happy Trails & Wag’n Tails will do our best to ensure that information presented is accurate and up-to-date. Happy Trails & Wag’n Tails does not accept any responsibility for damages, loss or illness which may arise in connection with the use of the information published on this website. The decision to use, or not to use, any information is the sole responsibility of the reader. Opinions expressed here are those of individual contributors. © Happy Trails & Wag’n Tails, 2006-2018. All Rights Reserved.


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Jack PhillipsHappy Trails & Wag'n TailsSandy MejeanDEANNA HERRERAEmilee Recent comment authors
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Sandy Mejean
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Sandy Mejean

Is it safe to just stop giveing my dog trifexis? What is detox and do you have to do it?

DEANNA HERRERA
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DEANNA HERRERA

I will never give my dog triflexis again. She’s so sick costing us 100.00,s of dollars at vet trying to get her well. I’m so upset.

Emilee
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Emilee

I just recently got a lab, spaniel, terrier puppy who is now 10 weeks old. At his first vet appointment, he was just 8 weeks and 10.6 pounds, they gave us a dose of Trifexis. One week later, Murphy had 3 seizures in one day. SO scary! We took him in and all tests came back clear… heart, blood, liver. They now have him on a seizure medication. We go to a neurologist next week… Could these episodes be from Trifexis!?! Should I do a detox on him?? Please help! He’s such a young sweet little pup. He definitely seems… Read more »

Willie F Jackson
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Willie F Jackson

I used Trifexis on my 2 yorkies that have always got alone. After using the product they have gotten very aggresive torwards each on the 2nd day. The 1st day they were very slump and laid back, wouldn’t jump, play, walk or bark, and wouldn’t even eat. Will never use this product again.

Leia Crowe
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Leia Crowe

My dog is 2 and she’s a 55lb staff. Never had a problem with trifexus except the last 2 times I’ve given it to her, hours later she starts to shake and tremble and fall asleep sitting up. This lasts for about 8hrs then she’s fine. I’m going to stop her trifexus and find soemthing else. But 10 days now after her last dose she woke up limping and acting lethargic. She’s at the vet now getting tests done. The vets all claim they’ve never heard of trifexus hurting dogs. I don’t know what else to put her on now,… Read more »

Pat King
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Pat King

I gave my Aussie Triflexis and she has developed skin rash, scabs what can I do for her

Sylvia &Denny
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Sylvia &Denny

My vet recommended Trifexis for my goldador several years ago and he started having seizures. Once I realized what was causing the seizures it is listed as one of the side effects in the precautions I took him off of it and begged everyone else who was using it to please change meds. My dog stopped having seizures and is now a certified therapy dog visiting nursing homes, hospitals and schools and making many people smile. Thank goodness we caught it in time or it may have killed this wonderful dog.

Leia Crowe
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Leia Crowe

My dog has started shaking after I give her trifexus… I’m taking her off it. What did you switch to?

Rene Johnson
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Rene Johnson

What did you do for the tremors?

Jack Phillips
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Jack Phillips

Hi Rene – my dog is experiencing the same tremors 10 days after our first pill of Trifexis…Did your pup recover? we are at a loss and she can’t sleep 🙁

B Wright
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B Wright

I wish I had know about the detox sooner, our Lab became so aggressive we had to put him down. He attacked me and my husband, It was devastating. He was almost 3 yrs old and we had him since he was a puppy, spoiled he went everywhere with us. The vet told us it had nothing to do with the Trifexis. the should be sued for still having this on the market!

Tammy Huffaker
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Tammy Huffaker

I have a 16 month old Chocolate Lab & she has had 2 doses of Trifexis & is not doing well!!! She is whining & crying, biting at her back, itching, lethargic, not eating well, disoriented, excessive salivating, panting, fever, trembling etc… what can I do to get this poison out??? PLEASE HELP

Shelby
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Shelby

I gave all 3 of our Argentine Dogos a dose of Trifexis yesterday. The 6 month old pup and the 2 year old dad seem to be doing okay with no side effects. Abby, our mama dog who is just over 2 on the other had is suffering from lethargy. She falls asleep while sitting up, she looks dazed and confused most of the time and refuses to put weight on her hind legs. I am so upset that I didn’t research (which I ALWAYS do) on this drug before giving this to Abby. I am so worried she will… Read more »

Tammy Huffaker
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Tammy Huffaker

My 16 mos old Chocolate Lab is doing the same things, it’s horrible, I wish I had never gave her this drug!!!!

jessica
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jessica

dosed my frenchie with trifexis today and several hours later she became aggressive and bit me. she already has some food aggression issues and has bitten us 3 times and I am not 100% but I think the previous 2 issues have been the day of or around the trifexis dosing. Anybody else have any experience with this? I am going to be contacting the company and all the blogs etc I can hit in order to get this out there. Am I blaming the trifexis for the bites? Possibly so. The resource guarding and aggression is a long standing… Read more »

Lynn
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Lynn

This Trifexis is horrible! I dosed my 62lb Boxer..within hours, she was so lethargic she couldn’t keep her eyes open. I feel horribly guilty for not doing the research after my vet recommended it. I’ve ordered the liver detox and will NEVER use Trifexis again. Why my Vet didn’t express any concerns with this product puzzles me.

Dawn
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Dawn

What did you give your dog for the liver detox, did it work and where can I get it please?!

Susan Williams
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Susan Williams

My shihtzu has been having seizures through which he howls as though in excrutiating pain. His whole body collapses in the floor as his head and back are in an impossible appearing arch. During this time his bowels and bladder are released. Shortly after, his rigidness relaxes and he lays inert. When he attempts to roll into an upright position, it takes several attempts. On 3/20/15 he had 3 in a 10 hour period in the afternoon to early morning of the next day.

Lilly
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Lilly

I am very worried about my Boxer, We gave her Trifexis Tablet and she is not eating very lethargic

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